• Do I have the right target?
• How should my drug look like?
• Which is the best lead to be further explored?
• How to analysis in-vivo and pharmacokinetic (PK) data?
• I don´t know how to write an investigator brochure for a phase 1 study.
GPRS provides
• Target analysis.
• Druggability analysis and rating.
• Establish target product profile (TPP).
• Selection of advanced lead compounds for in-vivo studies.
• Analysis and calculation of PK-data (WinNonlin).
• Selection of new investigation drug (IND).
• Build-up fall back or back-up strategy.
• Support writing of reports and investigator brochures.
Institutional Research Groups or NGOs
Free initial consulting
for Institutional Research Groups and Start-up companies.
You need to know
• I don´t know the target of my drug / hit.
• Which compounds should I select?
• How to analysis my screening data?
• Should I do a new screening, explore hit or stop?
• Where is my drug binding. What is the mode of action?
• How to do rational drug design on my screening hit?
• What do I need for my first in-vivo studies and proof of concept studies.
GPRS provides
• Disease pathway analysis from genes or proteins.
• Compound selection for screening assays from reliable suppliers.
• Full structure-activity report (SAR) analysis of screening data.
• Suggest new screening compounds – scaffold hopping.
• Support binding site elucidation. Suggest mode of action experiments.
• Provide full molecular design package.
• Guide lead optimization to enable first in-vivo studies and prove of concept studies.
Start-up companies
You need to know
• How to build-up and review business strategy?
• Who are our competitors?
• What are they doing?
• How to present your new venture to investors and customers?
GPRS provides
• Evaluate business strategy.
• Market and customer analysis.
• SWOT analysis.
• Support in the preparation of company presentation.
Investors and investment bankers
You need to know
• What is the scientific rational of the new venture?
• Are there potentially hidden risks?
• What makes it unique?
GPRS provides
• Review of the scientific landscape
• Critical path analysis.
• Competitor analysis.
